In the historical context of a crisis in biological psychiatry, psychedelic drugs paired with psychotherapy are globally re-emerging in research clinics as a potential transdiagnostic therapy for treating mood disorders, addictions, and other forms of psychological distress. The treatments are poised to soon shift from clinical trials to widespread service delivery in places like Australia, North America, and Europe, which has prompted ethical questions by social scientists and bioethicists. Taking a broader view, we argue that the ethics of psychedelic therapy (...) concerns not simply how psychotherapies are different when paired with psychedelic drugs, but how psychedelic therapies shape and are shaped by different values, norms, and metaphysical commitments. Drawing from the published literature and interviews with seven psychedelic therapists working in clinical trials in the United States, Germany, Switzerland, and Australia, this article opens the black box of the treatments to consider the values and informal debates currently animating the therapies. Considering questions of patient autonomy, mechanisms of therapeutic action, and which therapies are best suited to pair with psychedelic substances, we examine the ethics of psychedelic therapy as an emergent form of life. To bring this form of life out in fuller relief, we conclude by comparing and contrasting it with ayahuasca use in Amazonian shamanism. (shrink)

Using an economic bargaining game, we tested for the existence of two phenomena related to social norms, namely norm manipulation – the selection of an interpretation of the norm that best suits an individual – and norm evasion – the deliberate, private violation of a social norm. We found that the manipulation of a norm of fairness was characterized by a self-serving bias in beliefs about what constituted normatively acceptable behaviour, so that an individual who made an uneven bargaining offer (...) not only genuinely believed it was fair, but also believed that recipients found it fair, even though recipients of the offer considered it to be unfair. In contrast, norm evasion operated as a highly explicit process. When they could do so without the recipient's knowledge, individuals made uneven offers despite knowing that their behaviour was unfair. (shrink)

An axiomatic treatment of synthetic domain theory is presented, in the framework of the internal logic of an arbitrary topos. We present new proofs of known facts, new equivalences between our axioms and known principles, and proofs of new facts, such as the theorem that the regular complete objects are closed under lifting . In Sections 2–4 we investigate models, and obtain independence results. In Section 2 we look at a model in de Modified realizability Topos, where the Scott Principle (...) fails, and the complete objects are not closed under lifting. Section 3 treats the standard model in the Effective Topos. Theorem 3.2 gives a new characterization of the initial lift-algebra relative to the dominance. We prove that in the standard case it is not the internal colimit of the chain 0 → L → L 2 → ⋯ . The models in Sections 2 and 3 compare via an adjunction. Section 4 discusses a model in a Grothendieck topos. A feature here is that N is not well-complete , whereas 2 is. (shrink)

Graphical AbstractScience and technology consortia provide a viable solution for the recent unsustainable academic growth in biomedical research.

This paper presents an implemented computational model of word acquisition which learns directly from raw multimodal sensory input. Set in an information theoretic framework, the model acquires a lexicon by finding and statistically modeling consistent cross‐modal structure. The model has been implemented in a system using novel speech processing, computer vision, and machine learning algorithms. In evaluations the model successfully performed speech segmentation, word discovery and visual categorization from spontaneous infant‐directed speech paired with video images of single objects. These results (...) demonstrate the possibility of using state‐of‐the‐art techniques from sensory pattern recognition and machine learning to implement cognitive models which can process raw sensor data without the need for human transcription or labeling. (shrink)

Virtue ethics is regarded as the key in search of moral excellence among corporations. Yet, there are limited works to empirically investigate what virtuous character morally good corporations is expected to exhibit in the course of business from the perspective of customers. To fill this gap, we argue that customers are to evaluate firm’s virtuous character using Confucian cardinal virtues (ren, yi, and li) and perceived virtuousness determines customer loyalty. We test this argument using a sample of 276 Hong Kong (...) Chinese. The result suggests that a corporation not only has to offer a good value and high quality to customers but also needs to develop and acquire virtuous character in retaining customer loyalty. Firm has to embrace ren, yi, and li as the primary business goal. In fact, they are not the means but the end in themselves. The continuous pursuit of these cardinal virtues at the firm level not only establishes proper corporate values but also enables a firm to act morally in the course of business. Such kind of firm is known as junzi corporation. (shrink)

The American Journal of Bioethics, Volume 11, Issue 6, Page 55-57, June 2011.

In this work, we propose a variant of so-called informational semantics, a technique elaborated by Voishvillo, for two infectious logics, Deutsch’s |${\mathbf{S}_{\mathbf{fde}}}$| and Szmuc’s |$\mathbf{dS}_{\mathbf{fde}}$|⁠. We show how the machinery of informational semantics can be effectively used to analyse truth and falsity conditions of disjunction and conjunction. Using this technique, it is possible to claim that disjunction and conjunction can be rightfully regarded as such, a claim which was disputed in the recent literature. Both |${\mathbf{S}_{\mathbf{fde}}}$| and |$\mathbf{dS}_{\mathbf{fde}}$| are formalized in (...) terms of natural deduction. This allows us to solve several problems: to develop a natural deduction calculus for |${\mathbf{S}_{\mathbf{fde}}}$| containing the standard form of disjunction elimination (in contrast to the calculus by Petrukhin), to introduce the first natural deduction calculus for |$\mathbf{dS}_{\mathbf{fde}}$| and to reflect the fundamental symmetry between |${\mathbf{S}_{\mathbf{fde}}}$| and |$\mathbf{dS}_{\mathbf{fde}}$| on proof-theoretical level forming a convenient basis for obtaining their well-known extensions |$\mathbf{K}^{\mathbf{w}}_{\mathbf{3}}$| and |$\mathbf{PWK}$|⁠. (shrink)

We show, that given two fundamental theses of Kripke, no statement of the form ‘‘a=b’ is necessarily true’, is true, if ‘a’ and ‘b’ are distinct rigid designators.

The slogan that rationality is about responding to reasons has a turbulent history: once taken for granted; then widely rejected; now enjoying a resurgence. The slogan is made harder to assess by an ever-increasing plethora of distinctions pertaining to reasons and rationality. Here we are occupied with two such distinctions: that between subjective and objective reasons, and that between structural rationality (a.k.a. coherence) and substantive rationality (a.k.a. reasonableness). Our paper has two main aims. The first is to defend dualism about (...) rationality – the view that affirms a deep distinction between structural and substantive rationality – against its monistic competitors. The second aim is to answer the question: with the two distinctions drawn, what becomes of the slogan that rationality is about responding to reasons? We’ll argue that structural rationality cannot be identified with responsiveness to any kind of reasons. As for substantive rationality, we join others in thinking that the most promising reasons-responsiveness account of substantive rationality will involve an “evidence-relative” understanding of reasons. But we also pose a challenge for making this idea precise – a challenge that ultimately calls into question the fundamentality of the notion of a reason even with respect to the analysis of substantive rationality. (shrink)

Comment on Declan Smithies's book The Epistemic Role of Consciousness (2019).

Inhaltsverzeichnis/Contents: H.G. CALLAWAY: Open Transcendentalism and the Normative Character of Methodology. Roger F. GIBSON: Two Conceptions of Philosophy. Jürg FREUDIGER: Quine und die Unterdeterminiertheit empirischer Theorien. David PEARS: The Ego and the Eye: Wittgenstein's Use of an Analogy. Guido KÜNG: Welterkennen und Textinterpretation bei Roman Ingarden und Nelson Goodman. Barry SMITH: Putting the World Back into Semantics. Herbert STACHOWIAK: Offen für Ophelia? Paul GOCHET & Michel KEFER: Henri Lauener's Open Transcendentalism. Rudolf HALLER: Zum Problem des Relativismus in der Philosophie. Andreas (...) GRAESER: Analytic Philosophy and Hermeneutic Philosophy. Toward Reunion in Philosophy? Avrum STROLL: That Puzzle We Call the Mind. Wolfgang RÖD: Humes Skeptizismus als Entwurf eines neuen philosophischen Paradigmas. Henry E. ALLISON: Apperception and Analyticity in the B-Deduction. Peter SIMONS: Who's Afraid of Higher-Order Logic? Wilhelm K. ESSLER: Gorgias hat Recht! Alex BURRI: Relativismus, Realismus, Mathematik. (shrink)

This paper argues that nothing that has been discovered in the increasingly complex delails of gene regulation has provided any grounds to retract or qualify Crick's version of the central dogma. In particular it defends the role of the genes as the sole bearers of information, and argues that the mechanism of epigenetic modification of the DNA is but another vindication of Crick's version of the central dogma. The paper shows that arguments of C.K. Waters for the distinctive causual role (...) of the genes are equivalent in important respects to the present ones and concludes with a defense of the informational role of the genes against an argument from trans-actĭng genetic regulation due to Stotz. (shrink)

We give three counterexamples to the folklore claim that in an arbitrary theory, if a complete type p over a set B does not divide over $C\subseteq B$, then no extension of p to a complete type over $\operatorname {acl}(B)$ divides over C. Two of our examples are also the first known theories where all sets are extension bases for nonforking, but forking and dividing differ for complete types (answering a question of Adler). One example is an $\mathrm {NSOP}_1$ theory (...) with a complete type that forks, but does not divide, over a model (answering a question of d’Elbée). Moreover, dividing independence fails to imply M-independence in this example (which refutes another folklore claim). In addition to these counterexamples, we summarize various related properties of dividing that are still true. We also address consequences for previous literature, including an earlier unpublished result about forking and dividing in free amalgamation theories, and some claims about dividing in the theory of generic $K_{m,n}$ -free incidence structures. (shrink)

This review examines Alex Csiszar's book, The Scientific Journal: Authorship and the Politics of Knowledge in the Nineteenth Century.

The attitude of intention is not usually the primary focus in philosophical work on self-knowledge. A recent exception is the so-called “Transparency” theory of self-knowledge, which attempts to explain how we know our own minds by appeal to reflection on non-mental facts. Transparency theories are attractive in light of their relative psychological economy compared to views that must posit a dedicated mechanism of ‘inner sense’. However, it is argued here, focusing on proposals by Richard Moran and Alex Byrne, that (...) the Transparency approach to explaining knowledge of our intentions fails. Considerations of economy therefore recommend an alternative approach: the Rylean Theory Theory. The particular view defended here is that one way of coming to know what we intend is to self-ascribe an intention on the basis of making a conscious decision about what to do. This view requires that there are such things as conscious decisions, and so the existence of conscious decisions is defended against skeptical worries raised by Peter Carruthers. The conclusion is that we know of our intentions by theorizing about ourselves, but that this knowledge can still be first-personally privileged, authoritative, and non-alienated. (shrink)

In this issue, Alex London and Kevin Zollman provide an analysis of an influential approach to the ethics of international research, known as the “fair benefits” approach. According to them, the fair benefits approach suffers from a fatal flaw: it is either too vague to be useful, or worse, is internally inconsistent. The fair benefits approach was developed based on a presentation I gave at a workshop organized in Malawi in March 2001 by the National Institutes of Health Clinical (...) Center’s Department of Bioethics. In this presentation, I made what I still think is a valid point, which was accepted by the diverse group of participants and formed the basis of the subsequent publications: One should not .. (shrink)

Review of Alex Byrne's book Transparency and Self-Knowledge.

Journal Name: Philologus Issue: Ahead of print.

Traditionally, perceptual experiences—for example, the experience of seeing a cat—were thought to have two quite distinct components. When one sees a cat, one’s experience is “about” the cat: this is the representational or intentional component of the experience. One’s experience also has phenomenal character: this is the sensational component of the experience. Although the intentional and sensational components at least typically go together, in principle they might come apart: the intentional component could be present without the sensational component or vice (...) versa. (shrink)

Although decision‐making algorithms are not new to medicine, the availability of vast stores of medical data, gains in computing power, and breakthroughs in machine learning are accelerating the pace of their development, expanding the range of questions they can address, and increasing their predictive power. In many cases, however, the most powerful machine learning techniques purchase diagnostic or predictive accuracy at the expense of our ability to access “the knowledge within the machine.” Without an explanation in terms of reasons or (...) a rationale for particular decisions in individual cases, some commentators regard ceding medical decision‐making to black box systems as contravening the profound moral responsibilities of clinicians. I argue, however, that opaque decisions are more common in medicine than critics realize. Moreover, as Aristotle noted over two millennia ago, when our knowledge of causal systems is incomplete and precarious—as it often is in medicine—the ability to explain how results are produced can be less important than the ability to produce such results and empirically verify their accuracy. (shrink)

Intentionalism about demonstratives is the view that the referent of a demonstrative is determined solely by the speaker's intentions. Intentionalists can disagree about the nature of these intentions, but are united in rejecting the relevance of other factors, such as the speaker's gestures, her gaze, and any facts about the addressee or the audience. In this paper, I formulate a particular version of this view, and I defend it against six objections, old and new.

It has become an intellectual commonplace to claim that we have entered the era of 'postmodernity'. Three themes are embraced in this claim the poststructurist critique by Foucault, Derrida and others of the philosophical heritage of the Enlightenment the supposed impasse of High Modern art and its replacement by new artistic forms and the alleged emergence of 'post-industrial' societies whose structures are beyond the ken of Marx and other theorists of industrial capitalism. Against Postmodernism takes issue with all these themes. (...) It challenges the idealist irrationalism of post-structuralism. It questions the existence of any radical break separating allegedly Postmodern from Modern art. And it denies that recent socio-economic developments represent any fundamental shift from classical patterns of capital accumulation. Drawing on philosophy and history, Against Postmodernism takes issue also with some of the most forthright critics of postmodernism -- Jurgen Habermas and Fredric Jameson, for example. But it is most distinctive in that it offers a historical reading of the theories of such currently fashionable thinkers as Baudrillard and Lyotard. Postmodernism, Alex Callinios argues, reflects the disappointed revolutionary generation of '68, and the incorporation of many of its members into the porfessional and managerial 'new middle class'. It is best read as a symptom of political frustration and social mobility rather than as a significant intellectual or cultural phenomenon in its own right. (shrink)

Common principles for resource allocation in health care can prioritize the alleviation of small health burdens over lifesaving treatment. I argue that there is some evidence that these principles are at odds with a sizable share of public opinion, which holds that saving a life should take priority over any number of cures for minor ailments. I propose two possible explanations for this opinion, one debunking and one vindicatory. I also outline how well-designed surveys and moral inquiry could help decide (...) between them. Finally, I consider how priority-setting principles could be adjusted if the view that saving a life always trumps alleviating small burdens were vindicated. (shrink)

This essay surveys the varieties of disjunctivism about perceptual experience. Disjunctivism comes in two main flavours, metaphysical and epistemological.

This paper introduces a symposium on Equality versus Priority. It explains how cases involving risk are key to distinguishing these views and discusses a 'social egalitarian' critique of both 'telic egalitarians' and 'telic prioritarians'.

One very popular framework in contemporary epistemology is Bayesian. The central epistemic state is subjective confidence, or credence. Traditional epistemic states like belief and knowledge tend to be sidelined, or even dispensed with entirely. Credences are often introduced as familiar mental states, merely in need of a special label for the purposes of epistemology. But whether they are implicitly recognized by the folk or posits of a sophisticated scientific psychology, they do not appear to fit well with perception, as is (...) often noted. -/- This paper investigates the tension between probabilistic cognition and non-probabilistic perception. The tension is real, and the solution—to adapt a phrase from Quine and Goodman—is to renounce credences altogether. (shrink)

When A utters a declarative sentence in a context to B, typically A can mean a proposition by the sentence, the sentence in context literally expresses a proposition, there are propositions A and B can agree the sentence literally expressed, and B can acquire knowledge from this testimonial exchange. In recent work on linguistic communication, each of these four platitudes has been challenged, and on the same basis: viz. on the ground that exactly which proposition the sentence expressed in context (...) is not discernible given the information provided by the context. I argue that, even if this is true, there will be propositional parts of the proposition expressed by the sentence in context which can be identified and that, consequently, the partial understanding afforded by the existence of such identifiable parts undermines the soundness of the arguments against the platitudes. (shrink)

It seems possible to see a star that no longer exists. Yet it also seems right to say that what no longer exists cannot be seen. We therefore face a puzzle, the traditional answer to which involves abandoning naïve realism in favour of a sense datum view. In this article, however, I offer a novel exploration of the puzzle within a naïve realist framework. As will emerge, the best option for naïve realists is to embrace an eternalist view of time, (...) and claim that in the relevant case, one sees a still existent star‐stage located somewhere in the distant past. (shrink)

Darwin in Argentina -- Conflicting Systems -- Francisco Javier Muniz (1795-1871) -- Hermann Burmeister (1807-1891) -- Francisco P. Moreno (1852-1919) -- Domingo F. Sarmiento (1811-1888) -- Eduardo Holmberg (1852-1937) -- Florentino Ameghino (1854-1911) -- Jose Ingenieros (1877-1925) -- Carlos Octavio Bunge (1875-1918).